Press releases, publications and events.

Founding research

• 2014 · AgingMechanisms of action of hESC-secreted proteins that enhance human and mouse myogenesis Yousef H, Conboy MJ, Mamiya H, Zeiderman M, Schlesinger C, Schaffer DV, Conboy IM.
• 2013 · AginghESC-secreted proteins can be enriched for multiple regenerative therapies by heparin-binding Yousef H, Conboy MJ, Li J, Zeiderman M, Vazin T, Schlesinger C, Schaffer DV, Conboy IM.
• 2011 · AgingEmbryonic anti-aging niche Conboy IM, Yousef H, Conboy MJ.

Selected posters and presentations

• July 2025 · ENDO 2025Poster: JUV-161, an investigational fusion protein, in a mouse model of type 2 diabetes (ENDO 2025). (PDF)
• June 2024 · ENDO 2024Presentation at the Endocrine Society annual meeting: Jeremy O'Connell, Priya Handa and Ritwik Datta (image)
• March 2024 · MDA Clinical & Scientific ConferencePoster: preclinical development of JUV-161 for myotonic dystrophy type 1 (PDF)
• September 2023 · IPF Summit 2023Poster: secreted proteins from pluripotent stem cells and the function of lung alveolar cells under fibrotic stress (IPF Summit 2023). (PDF)
• June 2023 · Age-Related Disease Therapeutics Summit 2023Poster: an ML-enhanced platform that uses stem-cell secretomes to identify therapeutic proteins (5th Age-Related Disease Therapeutics Summit 2023). (PDF)
• July 2022 · FASEB Industry PanelPanel presentation by Jeremy O'Connell (PDF)

Selected literature on stem-cell secreted proteins

• 2022 · Translational NeurodegenerationAutologous treatment for ALS with implication for broad neuroprotection Kim D, Kim S, Sung A, Patel N, Wong N, Conboy MJ, Conboy IM.
• 2020 · Nature CommunicationsInhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis Dinh PC, Paudel D, Brochu H, et al.
• 2020 · Trends in BiotechnologyEmergence of the stem cell secretome in regenerative engineering Daneshmandi L, Shah S, Jafari T, et al.
• 2019 · Stem Cell Research & TherapyHarnessing the secretome of adipose-derived stem cells in the treatment of ischemic heart diseases Li X, Ma T, Sun J, et al.
• 2019 · npj Regenerative MedicineProteomic analysis of human mesenchymal stromal cell secretomes: a systematic comparison of the angiogenic potential Kehl D, Generali M, Mallone A, et al.
• 2017 · Stem Cells Translational MedicineMesenchymal stem cells: time to change the name! Caplan AI.
• 2016 · NeuroscienceMesenchymal stem cell-derived exosomes from different sources selectively promote neuritic outgrowth Lopez-Verrilli MA, Caviedes A, Cabrera A, Sandoval S, Wyneken U, Khoury M.