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  Hanadie Yousef is a trained stem cell biologist and neurobiologist with a focus on the mechanisms of aging, with pending and issued patents, several publications, a BS from Carnegie Mellon University (CMU), a PhD from UC Berkeley, a 4-year postdoctoral fellowship at Stanford School of Medicine, experience leading research teams, and has worked in R&D at Regeneron and Genentech.    Yousef began doing biomedical research at the age of 16, when she interned locally at a pharmaceutical company in New York where she grew up, Regeneron, to conduct research on gene therapy and cancer. It was at this time that Yousef fell in love with drug discovery and development and knew she wanted to dedicate the rest of her life to this pursuit. She skipped a grade and attended CMU to study chemistry and continue her passion in scientific research. She returned to Regeneron to continue her research during winter and summer internships for 5 years (2003-2008). During her undergraduate studies at CMU, Yousef did a research honors thesis in the Kaminski lab at the University of Pittsburgh Medical Center, where she elucidated molecular mechanisms driving idiopathic pulmonary lung fibrosis.    In graduate school in the Schaffer and Conboy labs at UC Berkeley (2008-2013), Dr. Yousef studied the role of adult stem cells in the biology of aging and developed methods for tissue rejuvenation in brain and muscle. She published 4 first-author papers, a research perspective,and has an issued patent and a patent application based on her discoveries.

nicole fay, PHD
life sciences consultant

Nicole Fay, PhD, Life Sciences Consultant with Juvena Therapeutics since March 2018, is managing the company's in vivo and analytics CRO endeavors. She is also advising on biotechnology preclinical path to IND strategies, quality control, and diligence-related documentation.

Nicole has worked as an independent consultant since 2014, where she advised early stage life sciences companies, VC firms and patent firms as a scientific specialist. In addition to consulting, she was the 2nd employee at Applied Molecular Transport (AMT), a biotechnology start-up focused on targeted oral biological therapeutics. While Nicole was a Senior Scientist/Scientist there, she worked on therapeutics for autoimmune and metabolic diseases, including growth hormone-related disorders. 

Prior to AMT, Nicole was at the University of California at Berkeley (UCB), completing a Biotechnology Management of Technology Certification program at Haas Business School, a post-doc in Biophysics, and a Ph.D. in Molecular & Cell Biology. At UCB, Nicole focused on engineering recombinant immuno-modulatory fusion proteins to control ex vivo lymphocyte cellular fate, taking a novel, image analytics-based approach. Nicole's initial research experience began as an undergraduate in 2005 at the Georgia Institute of Technology, where she had the opportunity to work in several labs ranging from a D. rerio neurobiology lab (at Cornell University) to a biophysical lab studying transcytosis. Nicole's research experiences have been captured in publications, presentations at national conferences, and via awards (see links below). Nicole's science outreach has been featured on-line and you can find Nicole as a regular invited speaker on UCB campus.

Since Nicole's initial research experience studying cellular adaptation, she continues to translate molecular signaling events into novel therapeutic programs. In this arena, Nicole knows her work on recombinant protein-based drugs will have the greatest potential to revolutionize modern medicine. While working with the Juvena Therapeutics team, Nicole is happy to to help develop new, regenerative medicines that can repair muscle injury, treat sarcopenia, increase healthspan,  and vastly improve quality of life for our elderly population.