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  Hanadie Yousef is a trained stem cell biologist and neurobiologist with a focus on the mechanisms of aging, with pending and issued patents, several publications, a BS from Carnegie Mellon University (CMU), a PhD from UC Berkeley, a 4-year postdoctoral fellowship at Stanford School of Medicine, experience leading research teams, and has worked in R&D at  Regeneron and Genentech.    Yousef began doing biomedical research at the age of 16, when she interned locally at a pharmaceutical company in New York where she grew up, Regeneron, to conduct research on gene therapy and cancer. It was at this time that Yousef fell in love with drug discovery and development and knew she wanted to dedicate the rest of her life to this pursuit. She skipped a grade and attended CMU to study chemistry and continue her passion in scientific research. She returned to Regeneron to continue her research during winter and summer internships for 5 years (2003-2008). During her undergraduate studies at CMU, Yousef did a research honors thesis in the Kaminski lab at the University of Pittsburgh Medical Center, where she elucidated molecular mechanisms driving idiopathic pulmonary lung fibrosis.    In graduate school in the Schaffer and Conboy labs at UC Berkeley (2008-2013),  Dr.  Yousef studied the role of adult stem cells in the biology of aging and developed methods for tissue rejuvenation in brain and muscle. She published 4 first-author papers, a research perspective,and has an issued patent and a patent application based on her discoveries.
 
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ASHLEY BURKE
RESEARCH ASSOCIATE

Ashley Burke is a biologist with a BS from Stanford University. Ashley fell in love with research while working in the laboratory of Tony Wyss-Coray in the Department of Neurology at Stanford School of Medicine.

Under the guidance of her postdoc mentor Dr. Hanadie Yousef, Ashley completed an honors thesis in which she explored the mechanisms underlying the inhibitory effects of the aged systemic milieu on hippocampal neurogenesis (co-authorship on manuscript in review at Nature Medicine, oral presentation at Achauer Undergraduate Honors Symposium).

During the last year of her undergraduate studies, Ashley also did a 6-month co-op internship at Biogen in Technical Development, working on a proof-of-concept study aimed at simplifying the development of therapeutic cell lines. Ashley’s research in the Wyss-Coray lab and at Biogen has bolstered her interest in the molecular biology of aging, stem cell regulation, inflammation, and degenerative disease, and she is excited to help Juvena bring life-changing therapies to people in need.


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